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October 2017

Across the Consortium – October 2017

Oct. 19, 2017:

As the Big Ten CRC leads the rapidly-changing world of cancer research, Across the Consortium is your one-stop source for the latest. From technologies to funding, and from public health to discoveries we hand-pick the breaking stories so you don’t miss a thing!

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Big Ten Cancer Researchers Hold Summit in Chicago

Oct. 19, 2017:

Researchers and leaders from 12 Big Ten cancer centers will meet at Big Ten Conference Headquarters in Chicago on Saturday. The Big Ten Cancer Research Consortium Summit is expected to draw about 150 participants, including researchers from across the consortium and representatives from pharmaceutical and biotech companies. The University of Illinois Cancer Center and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University are co-hosting the meeting. Read More

Member feature: Fred & Pamela Buffett Cancer Center

Oct. 1, 2017:

Investigator Spotlight

Hamid Band, MD, PhD, Fred & Pamela Buffett Cancer Center

Educational background: M.D. Medical College, Srinagar,, Kashmir University, India; Ph.D. Immunology, All-India Insitute of Medical Sciences, New Delhi, India

Research interests: Our research focuses on two major topics, both geared to understand, and potentially target, the intracellular traffic of cell surface receptors coupled to activation of tyrosine kinase signaling: the CBL-family of ubiquitin ligases, which provides an essential mechanism of negative regulation of receptor and non-receptor tyrosine kinases through ubiquitin-dependent proteasomal and lysosomal degradation; and members of the EHD family of endocytic regulatory proteins, which control subcellular traffic of cell surface receptors involved in a variety of fundamental cellular processes. We use mouse genetic models, cell biology, biochemistry and molecular biology approaches to investigate the roles of these protein families in the context of epithelial (mammary and intestinal) and hematopoietic stem cell homeostasis, immune responses in cancer, and tumor progression and metastasis in breast cancer and myeloid leukemia. A newer interest in the laboratory is on cancer immunology, with a focus on enhancing the efficacy of CAR T-cell immunotherapy of solid tumors.

Little-known facts about Dr. Band: 

  • As a child, I walked a mile and a quarter each way to attend middle school, rain or shine. Thank God, they gave us six weeks off in winter.
  • In 1980/1981, I applied to Ph.D. programs at five U.S. universities and was rejected by all. About eight years later (three years after receiving my official Ph.D. degree from India), I accepted my first Ph.D. student and taught a course in immunology at one of those universities — Harvard.
  • Except for Wheatfield’s Bakery in Omaha, I rarely buy foods without scanning the nutritional information on the package.

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