Jan. 29, 2018:
Breast cancer researchers have made great strides in recent years, identifying distinct molecular subtypes of the disease and potential novel treatment approaches. One such approach involves a type of immunotherapy, called an immune checkpoint inhibitor, that can help the immune system recognize and kill cancer cells.
Immune checkpoint inhibitors have shown promising results in a variety of research studies, and have been approved by the U.S. Food and Drug Administration to treat a variety of other cancers.In breast cancer research, much attention has been focused on triple-negative disease, or cancers in which the three most common receptors that fuel breast cancer growth – estrogen receptor, progesterone receptor, and the HER2/neu gene – are not present. A number of studies are now testing checkpoint inhibitors in triple negative breast cancer.
“But sometimes we get so focused on one subgroup, that we forget about the hormone-positive breast cancers,” said Deborah L. Toppmeyer, MD, of the Rutgers Cancer Institute of New Jersey. Read More
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